Clearview Eye and Laser Medical Center
Monday, March 31, 2008
New Trial May Restore Vision
Six years after using the same method to restore sight in congenitally blind dogs, researchers at the universities of Florida and Pennsylvania have begun a human gene therapy trial. If it works as well as in humans as it has in dogs then it might one day give ophthalmologists the means to cure blindness caused by “missteps” along the eye’s molecular pathways.
The trial is a phase one human safety study, and there is a small chance that the first patients involved in the trial will have some of their vision restored. In puppies, the gene therapy actually showed results within one to two months.
In the next year, six adults and three children (8-17), with Leber’s congenital amaurosis are to receive the gene therapy over the next year. People with LCA often have severe loss of vision from birth or early childhood, complete night blindness, extinguished rod electroretinography and severely reduced cone responses.
To learn more about advances in ophthalmology or to see about having LASIK, please contact the office of Clearview Eye and Laser Medical Center in San Diego, California.
The trial is a phase one human safety study, and there is a small chance that the first patients involved in the trial will have some of their vision restored. In puppies, the gene therapy actually showed results within one to two months.
In the next year, six adults and three children (8-17), with Leber’s congenital amaurosis are to receive the gene therapy over the next year. People with LCA often have severe loss of vision from birth or early childhood, complete night blindness, extinguished rod electroretinography and severely reduced cone responses.
To learn more about advances in ophthalmology or to see about having LASIK, please contact the office of Clearview Eye and Laser Medical Center in San Diego, California.
posted by Lynn at 9:00 AM
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Sandy T. Feldman, M.D., M.S. :: ClearView Eye and Laser Medical Center
6255 Lusk Blvd., Suite 100 :: San Diego, California 92121
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